10 free, exam-style Board Certified Sterile Compounding Pharmacist (BCSCP) practice questions with answers and
explanations. No signup required. Work through them below, then take the
full free BCSCP practice test to study every exam domain.
These 10 free BCSCP questions are organized by exam domain, so you can see how each part of the Board Certified Sterile Compounding Pharmacist blueprint is tested. Reveal the answer and explanation under each question.
Domain 1: Compounded Sterile Preparations 60% of exam
Question 1
A technician compounds a non-hazardous IV admixture using only sterile starting components inside an ISO Class 5 PEC located in a segregated compounding area (SCA). Under USP <797>, what is the MAXIMUM beyond-use date (BUD) that may be assigned if the preparation is stored under refrigeration?
- 24 hours
- 12 hours
- 4 days
- 10 days
Show answer & explanation
Correct answer: A - 24 hours
Question 2
An evaluator is performing a gloved fingertip and thumb sampling on a compounder immediately after the garbing competency. To obtain a valid result, the compounder's gloved hands should be sampled:
- After applying sterile 70% isopropyl alcohol and allowing it to dry
- After a 30-second alcohol-based surgical hand rub is reapplied
- Before sterile 70% isopropyl alcohol is applied to the gloves
- Only after the media-fill test has been completed and incubated
Show answer & explanation
Correct answer: C - Before sterile 70% isopropyl alcohol is applied to the gloves
Question 3
A pharmacy is designing a cleanroom suite to prepare sterile antineoplastic (hazardous) CSPs. Which combination of engineering controls is appropriate for this work?
- A horizontal laminar airflow workbench in a positive-pressure buffer room
- A compounding aseptic isolator in an unclassified segregated compounding area
- A powder containment hood vented into a positive-pressure ante-room
- A Class II biological safety cabinet (or CACI) in a negative-pressure C-SEC
Show answer & explanation
Correct answer: D - A Class II biological safety cabinet (or CACI) in a negative-pressure C-SEC
Question 4
Under the revised USP <797>, which statement about the order of garbing and hand hygiene when entering the cleanroom suite is correct?
- USP mandates one fixed national sequence that every compounding facility must follow exactly
- The specific order is set by the facility's SOP, but sterile gloves are always last
- Sterile gloves are donned first so the hands stay protected during gowning
- Hand hygiene is performed after gowning to avoid wetting the sterile gown
Show answer & explanation
Correct answer: B - The specific order is set by the facility's SOP, but sterile gloves are always last
Question 5
A compounder passes a heat-labile drug solution through a sterilizing-grade 0.22-micron membrane filter. Regarding the endotoxin (pyrogen) content of the filtered solution, this process:
- Destroys endotoxin because the filter physically retains pyrogens
- Both sterilizes and depyrogenates the solution in a single step
- Removes viable bacteria but does not reliably remove endotoxin
- Raises the endotoxin load by shedding particles from the membrane
Show answer & explanation
Correct answer: C - Removes viable bacteria but does not reliably remove endotoxin
Question 6
During compounding, a pharmacist records the specific lot numbers and expiration dates of each ingredient used, the personnel involved, the date of preparation, and the actual yield obtained for a particular batch. This information belongs in the:
- Compounding Record
- Master Formulation Record
- Safety Data Sheet
- Certificate of Analysis
Show answer & explanation
Correct answer: A - Compounding Record
Question 7
A pharmacist must prepare 250 mL of a 0.45% (w/v) sodium chloride solution but only has 23.4% (w/v) sodium chloride concentrate and sterile water for injection available. What volume of the 23.4% concentrate is required? (Use C1 x V1 = C2 x V2.)
- 2.4 mL
- 9.6 mL
- 11.7 mL
- 4.8 mL
Show answer & explanation
Correct answer: D - 4.8 mL
Domain 2: Therapeutics and Patient Management 15% of exam
Question 8
A patient receiving a peripheral infusion of a vesicant chemotherapy agent develops swelling, blanching, and burning pain at the IV insertion site, and the infusion slows. The nurse pauses the pump. This presentation is MOST consistent with:
- Phlebitis from chemical irritation of the vein wall
- A primary catheter-related bloodstream infection
- Extravasation of the vesicant into surrounding tissue
- Loss of catheter patency caused by a fibrin sheath
Show answer & explanation
Correct answer: C - Extravasation of the vesicant into surrounding tissue
Domain 3: Professional Practice 25% of exam
Question 9
A pharmacy technician skips disinfecting a vial stopper with sterile 70% IPA before puncture. Investigation shows the technician understood the requirement but routinely skipped it to save time because the omission was rarely noticed. Under a Just Culture framework, this is BEST classified as:
- Human error, calling for consolation and a redesign of the system
- A reportable sentinel event, calling for mandatory external disclosure
- Reckless behavior, calling for immediate disciplinary action
- At-risk behavior, calling for coaching and removing the incentive to skip
Show answer & explanation
Correct answer: D - At-risk behavior, calling for coaching and removing the incentive to skip
Question 10
A facility prepares large batches of sterile preparations in advance, without patient-specific prescriptions, and distributes them to hospitals as office stock. To operate this way, the facility must:
- Register with the state board only and follow USP <797> in place of cGMP
- Register as a 503B outsourcing facility and comply with cGMP
- Assign each batch to a single named patient on file before compounding
- Obtain a prescriber's verbal order for every unit within 72 hours of use
Show answer & explanation
Correct answer: B - Register as a 503B outsourcing facility and comply with cGMP